Article

It has always been something of a mystery as to why different diseases of the basal ganglia may produce completely opposite effects on movement. Thus, defective dopaminergic inhibitory input into the striatum in Parkinson's disease causes an akinetic-rigid syndrome, while destruction of the striatum in Huntington's disease usually causes chorea. This theoretic paradox may be resolved by more detailed examination of the exact sites of striatal damage in the two opposing conditions.

Langue : ANGLAIS

Tiré à part : OUI

Identifiant basis : 1986001042