Article

This study investigated the possible relationship between sensory recovery and receptor number after toe-to-hand transplantation. Moving two- point discrimination was measured after a course of sensory re-education. Meissner corpuscle number was then quantified by light microscopic examination of multiple sections of glabrous skin obtained at pulp reduction and from site-matched normal toe and fingertip skin. Meissner corpuscle number per millimeter was 0.94 in normal toe skin (n = 4), and 0.37 after toe-to-hand transplantation (n = 34). A significant correlation existed between moving two-point discrimination and Meissner corpuscle number (r = - 0.62; p < 0.001). No significant relationship was found between moving two- point discrimination and patient age or interval from injury to reconstruction. The results suggest that despite sensory re-education, there may be a level of receptor reinnervation below which good sensory recovery may not be obtained.

Langue : ANGLAIS

Tiré à part : OUI

Identifiant basis : 2001214853