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Evaluation of eutectic lidocaine/prilocaine cream (EMLA-R) for steroid joint injection in children with juvenile rheumatoid arthritis

UZIEL Y; BERKOVITCH M; GAZARIAN M
J RHEUMATOL , 2003, vol. 30, n° 3, p. 594-596
Doc n°: 109294
Localisation : Bibliothèque Universitaire de Médecine de Nancy
Descripteurs : DA525 - ARTHRITE JUVENILE

Objective. To evaluate the efficacy of eutectic lidocaine/prilocaine cream (EMLA((R))) in reducing the pain associated with steroid joint injection in children with juvenile arthritis. Methods. A randomized, double blind, placebo controlled parallel group trial. Thirty-one children (ages 8-18 yrs) scheduled for steroid injection into a knee were randomized into groups having either 2.5 g lidocaine/prilocaine cream or placebo cream applied to the injection site 60-90 min before the procedure. Patients assessed the pain associated with initial needle insertion and subsequent steroid injection using a 10 cm visual analog scale. Results. No significant difference was found in the pain reported after needle insertion or steroid injection between the lidocaine/prilocaine cream group (n = 17) and the placebo group (n = 14). There was a trend toward an association of lower median scores with the pain of steroid injection in the lidocaine/prilocaine group (6 min) compared with the placebo group (22 mm). Conclusion. Application of 2.5 g lidocaine/prilocaine cream for 60-90 min had no statistically significant analgesic effect on pain associated with injections of steroids into the knees of children with juvenile arthritis.

Langue : ANGLAIS

Identifiant basis : 2003227392

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