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Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke
SHIMIZU T; HOSAKI A; HINO T
BRAIN , 2002, vol. 125, n° 8, p. 1896-1907 Doc n°: 105638 Localisation : Documentation IRR Descripteurs : AF21 - ACCIDENTS VASCULAIRES CEREBRAUX Following a hemispheric stroke, various degrees of neuronal reorganization around the lesion occur immediately after disease onset and thereafter up to several months. These include transcallosal excitability, changes of the intact motor cortex and ipsilateral motor responses after transcranial magnetic stimulation (TMS) on the intact hemisphere. To elucidate the relationship between lesion localization and motor cortex excitability (intracortical inhibition; ICI) in the intact hemisphere, we applied a paired conditioning-test TMS paradigm in 12 patients with unilateral cortical stroke (cortical group) and nine patients with subcortical stroke caudal to the corpus callosum (subcortical group), with interstimulus intervals varying from 1 to 10 ms. All patients exhibited unilateral complete hand palsy. ICI was significantly less in the cortical group than in age-matched healthy control subjects. Langue : ANGLAIS Tiré à part : OUI Identifiant basis : 2002223709 |
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