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Treatment of adductor spasticity with BTX-A in children with CP

MALL V; HEINEN F; SIEBEL A; BERTRAM C; HAFKEMEYER U; WISSEL J; BERWECK S; HAVERKAMP F; NASS G; DODERLEIN L; BREITBACHFALLER N; SCHULTEMATTLER W; KORINTHENBERG R
DEV MED CHILD NEUROL , 2006, vol. 48, n° 1, p. 10-13
Doc n°: 124057
Localisation : Documentation IRR
Descripteurs : AJ23 - PARALYSIE CEREBRALE, AD32 - SPASTICITE

Adductor spasticity in children with cerebral palsy (0) impairs motor function and development. In a placebo-controlled, double-blind, randomized multicentre study, we evaluated the effects of botulinum. Toxin A (BTX-A) in 61 children (37 males, 24 females; mean age 6 years 1 month [SD 3y 1mo]) with CP (leg-dominated tetraparesis, n=39; tetraparesis, n=22; GMFCS level 1, n=3; II,
n=6; 111, n=17; IV, n=29; V, n=6). Four weeks after treatment,
a significant superiority of BTX-A was observed in the primary outcome measure (knee-knee distance 'fast catch', p=0.002), the Ashworth scale (p=0.001), and the Goal Attainment Scale (p=0.037).

Langue : ANGLAIS

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