Article

Focal hand dystonia is a disabling movement disorder, often
task specific, that leads to impaired hand use.
In addition to a genetic
predisposition, environmental risk factors including repetitive use and
musculoskeletal constraints are contributory. Although the underlying cause is
unknown, recent studies have identified several key mechanisms that may play a
part in its genesis. Failure of inhibition, abnormal sensorimotor integration,
and maladaptive plasticity seem to be important. Understanding the underlying
physiology may lead to the design of novel therapies.

Langue : ANGLAIS