Article

PURPOSE: To systematically evaluate the literature on quality of life and
adjustment to brain tumor from a biopsychosocial perspective. METHODS: On the
basis of the cancer and brain injury literature, a biopsychosocial organisational
framework was initially developed to support an evaluative review of the brain
tumor literature. This framework consisted of four themes relating to pre-illness
characteristics, neuropathology, personal appraisals and reactions and social
support. Electronic searches of Medline, PsycINFO and CINAHL databases identified
48 empirical studies (1980-2007) that investigated factors associated with
quality of life or the adjustment of adults with brain tumor. A review of studies
within each theme appraised these findings and evaluated the quality of
methodology and extent to which biopsychosocial perspectives have guided
investigations. RESULTS: Overall, the review identified consistent associations
between depression, performance status, fatigue and quality of life. Seven
multivariate studies with strong methodology that adopted a biopsychosocial
perspective were found. In general, the relationships among pre-illness and brain
tumor characteristics, psychosocial variables and quality of life were unclear
and various gaps in the literature emerged. CONCLUSIONS: Empirical findings
within a biopsychosocial perspective may guide the development and delivery of
support services for individuals with brain tumor; however, many important areas
exist for future research.

Langue : ANGLAIS