Article

Glioblastome - Tumeur - Gliome
A retrospective review of medical
records for patients admitted from September 1, 1996, to June 30, 2008, to the
inpatient rehabilitation unit at a tertiary care cancer center. A high-grade (21
of 443 patients) and low-grade astrocytoma (21 of 24 patients) group were matched
on three of five criteria in the order of importance: area of brain involvement
(divided into left cerebral, right cerebral, midline and/or bilateral cerebral,
and infratentorial), single vs. multiple intracranial neurosurgical procedures,
age (within 10 yrs), period of rehabilitation admission (within 3 yrs), and sex.
Descriptive statistics were used to compare demographic data and scores in four
categories (total, activities of daily living, mobility, and cognition) from the
patients' functional independence measure assessment. RESULTS: No significant (P
> 0.05) differences were found in demographics or efficiency between the two
groups. The high-grade group had significantly (P < 0.05) higher total gain and
longer stay in inpatient rehabilitation (mean +/- standard deviation, 21.7 +/-
10.1 vs. 13.0 +/- 9.3 and 13 +/- 7.1 day vs. 9 +/- 6.2 days, respectively) than
did the low-grade astrocytoma group. CONCLUSIONS: Compared with patients with
low-grade astrocytoma, patients with high-grade astrocytoma had higher total
functional independence measure gain but also longer lengths of stay. Functional
independence measure efficiencies were comparable between the two groups. Our
results parallel those of previous rehabilitation outcome studies comparing
patients with brain tumors with patients with brain injuries of other etiologies.
Larger matched studies are needed for this patient population.

Langue : ANGLAIS