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Paget's disease of bone : a review of epidemiology, pathophysiology and management
SHAKER JL
THER ADV MUSCULOSKEL DIS , 2009, vol. 1, n° 2, p. 107-125 Doc n°: 147448 Localisation : Documentation IRR Descripteurs : DA534 - MALADIE OSSEUSE DE PAGET, HB1 - EPIDEMIOLOGIE Paget's disease of bone is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. Fortunately, effective pharmacologic therapy, primarily with potent bisphosphonates, is now available to treat patients with complications or symptoms. This review of Paget's disease of bone will include epidemiology and pathophysiology, complications and clinical findings, indications for treatment, and the drugs currently available to treat this condition. Langue : ANGLAIS Tiré à part : OUI |
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