Article

Obésité - Béta bloquant -
Abstract : Cardiopulmonary exercise testing (CPET) is a widely applied clinical
procedure. There is uncertainty to what extent nutritional status, beta blockers
and smoking should be taken into account in the interpretation of exercise
parameters to describe abnormality. This study planned to consider the impact of
these factors on CPET values and develop reference equations on the basis of a
large-scale population-based survey. RESULTS: An incremental cycle
exercise protocol was applied to 1708 volunteers. Individuals with structural
heart disease, echocardiographic or lung function pathologies were excluded. Age,
height, weight, smoking, and beta blockers were analysed for their influencing
power in each sex. Reference values of CPET parameters were determined by
regression analyses. The final study sample consisted of 1203 volunteers (626
female), aged 25-85 years. Exercise capacity, gas exchange, and ventilatory
efficiency for carbon dioxide removal were significantly dependent on sex, age,
height, weight, and cigarette smoking. In the dosages used, beta blockers did not
significantly interfere with gas exchange. CONCLUSION:
Sex, height, weight, and
age significantly influence gas exchange. This study provides a comprehensive set
of reference values in a large number of volunteers within a population-based
survey, with reference values corrected for influencing factors.

Langue : ANGLAIS

Tiré à part : OUI