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Intrathecal baclofen in cerebral palsy. A retrospective study of 25
wheelchair-assisted adults = Baclofene intrathécal dans la paralysie cérébrale - Etude rétrospective de 25 patients adultes non marchants

TASSEEL PONCHE S; FERRAPIE AL; CHENET JP; MENEI P; GAMBART G; MENEGALLI BOGELI D; PERROUIN VERBE B; GAY S; RICHARD I
ANN PHYS REHABIL MED , 2010, vol. 53, n° 8, p. 483-498
Doc n°: 147943
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.rehab.2010.07.007
Descripteurs : AJ23 - PARALYSIE CEREBRALE

OBJECTIVE: To study the efficacy and safety of intrathecal baclofen therapy (ITB)
in wheelchair-dependent adults with cerebral palsy.
METHODS : A retrospective analysis and clinical examination of 25 wheelchair-assisted adults
with cerebral palsy receiving ITB initiated between 1999 and 2009 in three
different cities in western France. RESULTS: ITB improves spasticity and
facilitates wheelchair comfort and nursing care. The therapy has an effect on
motor disorders and pain. Eighty percent of the ITB patients were satisfied.
Dissatisfaction was related to complications or adverse events and not lack of
efficacy. Complications occurred in 32% of the patients and transient
interruption of the treatment or surgical removal of the ITB pump was necessary
in 16% of cases. CONCLUSION: Wider use of ITB in this indication
is likely and should lead to a better understanding of the drug's pharmacological
effects on motor disorders and pain. Use of the Goal Attainment Assessment Scale
or Caregiver Questionnaire can help us.
CI - Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS ; FRANCAIS

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