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Comparison between botulinum toxin and corticosteroid injection in the treatment of acute and subacute tennis elbow

LIN YC; TU YK; CHEN SS; LIN A; CHEN SC; GUO HR
AM J PHYS MED REHABIL , 2010, vol. 89, n° 8, p. 653-659
Doc n°: 147786
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1097/PHM.0b013e3181cf564d
Descripteurs : DD552 - PATHOLOGIE INFLAMMATOIRE COUDE

OBJECTIVE: To compare botulinum toxin type A injection with corticosteroid
injection in the treatment of tennis elbow. DESIGN: In this prospective,
randomized, double-blind, drug-controlled trial,19 affected elbows of 16 patients
were randomly assigned to receive injection with botulinum toxin type A (Botox
group) or triamcinolone acetonide (steroid group). We used the Visual Analog
Scale, pain-free grip strength, and World Health Organization Quality of Life
Brief Questionnaire to assess the perception of pain, grip strength, and quality
of life, respectively. Measures were performed before and at 4, 8, and 12 wks
after the treatment. RESULTS: Four weeks after the treatment, the Botox group had
smaller decrease in pain (P = 0.02) but greater decrease in grip strength (P =
0.01). The difference in grip strength remained significant at 8 wks (P = 0.03).
No significant differences in quality of life were observed throughout the study
period. CONCLUSIONS: Corticosteroid is superior to botulinum toxin type A in
relieving pain in tennis elbow at 4 wks after injection. Because botulinum toxin
injection did not relieve pain significantly but is associated with weakness, the
muscle weakness caused by botulinum toxin is unlikely to be the sole mechanism of
the pain relief observed in previous studies.

Langue : ANGLAIS

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