Article

Repetitive transcranial magnetic stimulation (rTMS) has been
recognized as a promising intervention for treatment of stroke patients. However,
most previous reports have described the short-term effects of rTMS on motor
performance. We conducted a sham-controlled trial to evaluate long-term effects
of high-frequency rTMS on motor recovery in subacute stroke patients. METHODS:
Twenty-eight patients were randomly divided into two groups, and received either
real or control rTMS. Both treatments were accompanied by motor practice. A daily
dose of 1000 pulses of subthreshold 10 Hz rTMS was applied over the primary motor
cortex of the affected hemisphere for 10 days within one month after onset of
stroke. Motor function was assessed before and after treatment, and 3 months
after the stroke. RESULTS: Motor function improved in both groups after
treatment; however, patients who received real rTMS experienced additional
improvement in motor function of the affected upper limb. Over 3 months after the
stroke, the time and type of intervention for the Motoricity Index of the
affected upper extremity showed significant interaction. CONCLUSION: Positive
long-term effects on motor recovery could be achieved after 10 daily sessions of
high-frequency rTMS in conjunction with motor practice during the sub-acute
period of stroke.

Langue : ANGLAIS