Article

Hemiplegic (or spastic unilateral) cerebral palsy accounts for
about 30% of all cases of cerebral palsy. With a population prevalence of 0.6 per
1000 live births, it is the most common type of cerebral palsy among term-born
children and the second most common type after diplegia among preterm infants.
Many types of prenatal and perinatal brain injury can lead to
congenital hemiplegia and brain MRI is the most useful tool to classify them with
accuracy and to provide early prognostic information. Perinatal arterial ischemic
stroke thus appears as the leading cause in term infants, whereas encephalopathy
of prematurity is the most common cause in premature babies. Other causes include
brain malformations, neonatal sinovenous thrombosis, parenchymal hemorrhage (for
example due to coagulopathy or alloimmune thrombocytopenia) and the more recently
described familial forms of porencephaly associated with mutations in the COL4A1
gene. PERSPECTIVES: In adjunction with pharmacologic treatment (botulinium
neurotoxin injection), new evidence-based rehabilitational interventions, such as
constraint-induced movement therapy and mirror therapy, are increasingly being
used.

Langue : FRANCAIS