Article

OBJECTIVE: To propose a predictive equation of the maximal work rate (Wmax) in
patients with chronic obstructive pulmonary disease (COPD) based on the product
of 6-minute walking test (6MWT) and fat-free mass (FFM) and to compare it with a
previously proposed equation based on the product of 6MWT and body weight (BW).
Descriptive (cross-sectional) study. SETTING: University-based
rehabilitation center. PARTICIPANTS: Patients with COPD (N=53; 30 men; forced
expiratory volume in 1 second, 45%+/-15% predicted). INTERVENTIONS: Not applicable.
MAIN OUTCOME MEASURES: Three Wmax were produced: Wmax_real (obtained
from the maximal cycle ergometry test), Wmax_BW (estimated from the product of
6MWT and BW), previously proposed by Hill et al. (Arch Phys Med Rehabil 2008;
89(9):1782-7); and Wmax_FFM (estimated from the product of 6MWT and FFM).
RESULTS: The equation derived from a regression model to estimate Wmax_FFM was as
follows: -27.9717+3.7792*(6MWT*FFM). Wmax_real correlated better with Wmax_FFM
(r=.64) than with Wmax_BW (r=.54). There was no difference between Wmax_FFM
(median [interquartile range], 41 [29-50] W) and Wmax_real (40 [20-50] W, P=.88),
whereas Wmax_BW (60 [52-69] W) significantly overestimated Wmax_real (P<.0001).
CONCLUSIONS: In patients with COPD, Wmax is better estimated by an equation
including the product of 6MWT and FFM than by a previously proposed equation
including the product of 6MWT and body weight.
CI - Copyright (c) 2010 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS