Article

This study examined the structural and external aspects of score
validity for the abbreviated Late Life-Function and Disability Inventory (LL-FDI)
as well as its longitudinal measurement invariance and responsiveness in
individuals with multiple sclerosis (MS). METHODS: The sample included 292
individuals with MS who completed a battery of questionnaires on two occasions
separated by 6 months. The battery included the abbreviated LL-FDI along with
measures of mobility disability; neurological impairments; symptoms of fatigue,
anxiety, depression and pain; health status; and quality of life. The data were
analysed using Analysis of Moment Structures (AMOS) and Statistical Package for
the Social Sciences (SPSS), versions 16.0. RESULTS: Confirmatory factor analysis
supported the structural validity and longitudinal measurement invariance of the
disability and functional limitations components of the abbreviated LL-FDI.
MANOVA and bivariate correlations supported the external aspects of score
validity based on differences in mean scores as a function of clinical MS course
(relapsing vs. progressive) and level of mobility disability (mild vs. moderate
mobility disability) and associations with measures of neurological impairments,
symptoms, health status and QOL, respectively. ANOVA established the
responsiveness (i.e., sensitivity for reflecting clinically important differences
in health status across time) of the functional limitations and disability
components of the abbreviated LL-FDI for detecting changes in mobility disability
across 6-months. CONCLUSION: Such findings provide a new option for the
measurement of functional limitations and disability using the abbreviated LL-FDI
in persons with MS.

Langue : ANGLAIS