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Clinical benefits of the addition of lower extremity low-intensity resistance muscle training to early aerobic endurance training intervention in patients with coronary artery disease

Muscle resistance training is often combined with aerobic endurance
training during rehabilitation of patients with coronary artery disease. However,
the clinical effects of additional lower-extremity low-intensity muscle
resistance training during early rehabilitation (within the first month after
coronary revascularization) in patients with coronary artery disease remain
unclear. Design: Prospective randomized controlled trial. Subjects: Sixty
patients with coronary artery disease. Methods: Subjects were randomly assigned
to early aerobic endurance training (n = 30) or combined aerobic endurance and
resistance muscle training (n = 30). Subjects performed 18 (standard deviation 2)
exercise sessions (at 65% VO2peak, for 40 mins/session).
In resistance muscle
training, additional low-intensity (12-20 repetition maximum) resistance muscle
exercises were performed.
The following parameters were evaluated: exercise
capacity, body composition, blood lipid profile, glycaemic control, blood
endothelial progenitor cell and cytokine content, and muscle performance.
Results: A total of 47 patients with coronary artery disease completed the
intervention. Total body lean tissue mass tended to increase with greater
magnitude (p = 0.07), and blood high-density lipid cholesterol content increased
with significantly greater magnitude in resistance muscle training (p < 0.05),
compared with aerobic endurance training. Maximal exercise capacity, ventilatory
threshold, and muscle performance increased, and steady-state exercise
respiratory exchange ratio, and adipose tissue mass reduced significantly (p <
0.05), without differences between groups (p < 0.05). Conclusion: In early
aerobic endurance training intervention in patients with coronary artery disease,
additional low-intensity resistance muscle training contributes to a greater
increase in blood high-density lipid cholesterol content, and tends to affect lean tissue mass.

Langue : ANGLAIS

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