Article

OBJECTIVES: To study the severity and 5-year course of fatigue in patients with
late-onset sequelae of poliomyelitis (LOSP) and to identify physical and
psychosocial determinants of fatigue. DESIGN: Prospective cohort study with 5
measurements over 5 years. SETTING: University hospital. PARTICIPANTS: Patients
with LOSP (N=168); 89% of the subjects completed the study. INTERVENTIONS: Not
applicable. MAIN OUTCOME MEASURES: Fatigue assessed with the Fatigue Severity
Scale (FSS). Potential determinants were perceived physical functioning, bodily
pain and mental health, extent of paresis, walking capacity, comorbidity,
sleeping disorders, coping, and social support. Associations were investigated by
multivariable longitudinal analysis using generalized estimating equations.
RESULTS: The mean FSS score +/- SD at baseline was 5.1+/-1.4, which did not
change significantly during the 5-year follow-up. Reduced physical functioning,
increased bodily pain, reduced sleep quality, more psychologic distress, and
higher task-oriented coping were independently associated with fatigue. The
extent of paresis and walking capacity were strongly associated with physical
functioning. CONCLUSIONS: Fatigue is severe and persistent in patients with LOSP
due to physical and psychologic factors, which has implications for counseling
and treatment. In addition to the commonly applied interventions targeting
physical aspects, psychologic interventions are a potential area for reducing
fatigue.
CI - Copyright (c) 2011 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS