Article

AIM: To determine the distribution of cognitive and motor scores in preterm
children, and to establish the influence of brain lesions and decreasing
gestational age thereon. METHOD: One hundred and six very preterm children (63
males, 43 females; gestational age 24.0-31.6 wk; birthweight 480-2275 g) were
assessed for cognition and motor outcome at 6 to 12 years. We assessed total,
verbal, and performance IQ using the Wechsler Intelligence Scale for Children,
and motor outcome using the Movement Assessment Battery for Children (Movement
ABC). RESULTS: The IQs and Movement ABC z-scores were normally distributed, but
shifted to the left. Mean total IQ (SD) was 91 (12), performance IQ 89 (13), and
verbal IQ 93 (15), being 0.60, 0.73, and 0.47 SD lower than the norm
respectively. Movement ABC z-scores were -1.27 SD lower (SD 1.01). IQ and
Movement ABC z-scores did not correlate with brain lesions or gestational age.
INTERPRETATION: The distribution curve for cognition and motor outcome at school
age is shifted to the left in preterm children, with an effect size of 0.60 SD
for IQ (nine IQ points) and 1.27 SD for motor outcome. These findings are
restricted to the current group. Developmental disruptions, affecting cerebral
white matter, cortex, cerebellum, and thalamus might be involved, although the
exact pathogenetic mechanism is unclear.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2011 Mac Keith
Press.

Langue : ANGLAIS