Article

The recent development of therapeutic approaches for Duchenne muscular dystrophy
(DMD) has highlighted the need to identify clinical outcome measures for planned
efficacy studies. Although several studies have reported the value of functional
scales, timed tests, and measures of endurance aimed at ambulant individuals,
less has been done to identify reliable measures of function in individuals who
have lost ambulation. The aim of this paper is to provide a critical review of
the existing literature on functional measures assessing upper extremity function
in DMD. Four observer-rated, performance-based measures and four self-reported
scales have been previously used in DMD. Each scale provides useful information
but none reflects all the different levels of functional ability in activities of
daily living observed in individuals with DMD at different ages.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2012 Mac Keith
Press.

Langue : ANGLAIS