Article

The aim of the Multiple Sclerosis Think Tank (Groupe de reflexion sur la sclerose
en plaques [GRESEP]) is to prescribe recommendations following a systematic
literature search and using a Rand Corporation and California University
(RAND/UCLA) appropriateness derived method, in response to practical questions
that are raised in the management of patients with multiple sclerosis (MS). The
topics of this working program were chosen because they were not addressed in the
French recommendations and because of the few data in the literature that enabled
practices to be based on validated data. Following the theme on useful serum
testing with suspected multiple sclerosis, the subjects of the present work
concern the detection and management of cognitive impairment in the beginning
stages of the disease course. Two clinical questions were asked: which
complementary exams (besides physical examination and neuropsychological tests)
would help in the screening of cognitive impairment at the beginning of the
disease? What care management should the person with MS and cognitive impairment
be offered (treatments and neurocognitive rehabilitation)? The recommendations
are the result of a consensus amongst a working group, a rating group and a
reading group comprised of hospital neurologists involved in the management of
patients with multiple sclerosis. Each recommendation is presented with the
degree of consensus that it was accorded.
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Langue : ANGLAIS