Article

Médecine basée sur les preuves -Translational research refers to the development of new scientific discoveries
into evidence-based treatments for human diseases and conditions. This
developmental process requires that a number of scientific, as well as social and
psychological obstacles, be overcome during a sequence of research stages that
address different goals. Rehabilitation, like other biomedical disciplines,
requires this kind of developmental process. For a variety of reasons, however,
development of rehabilitation treatments is less linear than the familiar phases
of pharmaceutical research. In addition, research on treatments intended to
address impairments (body structure/function, in terms of the International
Classification of Functioning, Disability and Health), faces the challenge of
determining the likely impact of an impairment-level treatment on the
multifaceted activities and aspects of participation that are the typical goals
of rehabilitation treatments. This article describes the application of treatment
theory and enablement theory to the development of new impairment-based
treatments, and examines similarities and differences between the developmental
sequence needed for rehabilitation treatment research versus pharmaceutical
research in other areas of medicine.
CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS