Article

PURPOSE: To summarize the potential origins of fatigue poststroke from a
neuromuscular perspective, including stroke-induced alterations at the cortical,
spinal and muscle levels. METHOD: Perspective based on narrative literature review. RESULTS: Fatigue is a highly prevalent, but poorly understood symptom
poststroke. Neuromuscular fatigue has central and peripheral origins. Individuals
with stroke experienced greater central fatigue and less peripheral fatigue
during voluntary contractions of the paretic leg in comparison to healthy
participants. Neuromuscular adaptations to stroke create an increased
susceptibility to central fatigue, which may be a contributing factor to the
increased perception of tiredness during performance of activities of daily
living. Future studies should investigate whether intervention-induced cortical
plasticity, gains in muscle strength and endurance will attenuate self-reported
fatigability. CONCLUSIONS: Fatigue is a common and debilitating consequence of
stroke. Neuromuscular fatigue of central origin may contribute to self-reported
fatigue. Continued focused and properly designed research studies should provide
substantial insight into the therapeutic interventions that will improve the management of fatigue poststroke.

Langue : ANGLAIS