Article

The aim of this study was to determine the relationship between parent and
child Full-scale IQ (FSIQ) in children with epilepsy and in typically developing
comparison children and to examine parent-child IQ differences by epilepsy
characteristics. Method The study participants were 97 children (50 males, 47
females; age range 8-18y; mean age 12y 3mo, SD 3y1mo) with recent-onset epilepsy
including idiopathic generalized (n=43) and idiopathic localization-related
epilepsies (n=54); 69 healthy comparison children (38 females, 31 males; age
range 8-18y; mean age 12y 8mo, SD 3y 2mo), and one biological parent per child.
All participants were administered the Wechsler Abbreviated Scale of Intelligence
(WASI). FSIQ was compared in children with epilepsy and typically developing
children; FSIQ was compared in the parents of typically developing children and
the parents of participants with epilepsy; parent-child FSIQ differences were
compared between the groups. Results FSIQ was lower in children with epilepsy
than in comparison children (p<0.001). FSIQ of parents of children with epilepsy
did not differ from the FSIQ of the parents of typically developing children.
Children with epilepsy had significantly lower FSIQ than their parents (p<0.001),
whereas comparison children did not. The parent-child IQ difference was
significantly higher in the group with epilepsy than the comparison group
(p=0.043). Epilepsy characteristics were not related to parent-child IQ
difference. Interpretation Parent-child IQ difference appears to be a marker of
epilepsy impact independent of familial IQ, epilepsy syndrome, and clinical
seizure features. This marker is evident early in the course of idiopathic
epilepsies and can be tracked over time.
CI - (c) The Authors. Developmental Medicine & Child Neurology (c) 2012 Mac Keith
Press.

Langue : ANGLAIS