Article

The purpose of this study was to evaluate the relationship between the recovery
of gross motor function and cerebrovascular reserve (CVR) capacity measured by
brain perfusion single-photon emission computed tomography (SPECT) in patients
with first-ever supratentorial infarction. Gross motor function was assessed
according to the locomotor and mobility subset of the functional independence
measure. The CVR was measured as the difference in the regional cerebral blood
flow (rCBF) after acetazolamide (ACZ)-challenged(99m)Tc-ECD perfusion SPECT from
baseline rCBF. All 22 hemiplegic patients (mean age, 60.97 years) enrolled were
admitted at a mean of 20.86 days from onset and received rehabilitation care for
an average of 38.82 days. The recovery of gross motor function was significantly
correlated with baseline rCBF and CVR of ACZ-SPECT in the areas of affected
supratentorial hemisphere (r=0.447 and r=0.444, respectively, p < 0.05). Analysis
of the linear regression model, adjusted for time to SPECT testing, revealed that
the CVR in the affected supratentorial hemisphere was a significant predictor of
the gross motor outcome (p< 0.05). In conclusion, the CVR of the affected
supratentorial hemisphere may be employed along with other parameters to predict
the gross motor recovery of patients with subacute infarction.

Langue : ANGLAIS