Article

Autism spectrum disorders (ASDs) are a group of heterogeneous neurodevelopmental
disorders that show impaired communication and socialization, restricted
interests, and stereotypical behavioral patterns. Recent advances in molecular
medicine and high throughput screenings, such as array comparative genomic
hybridization (CGH) and exome and whole genome sequencing, have revealed both
novel insights and new questions about the nature of this spectrum of disorders.
What has emerged is a better understanding about the genetic architecture of
various genetic subtypes of ASD and correlations of genetic mutations with
specific autism subtypes. Based on this new information, we outline a strategy
for advancing diagnosis, prognosis, and counseling for patients and families.
CI - (c) 2013 Mac Keith Press.

Langue : ANGLAIS