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Recovery from poststroke visual impairment : evidence from a clinical trials resource

ALI M; HAZELTON C; LYDEN P; POLLOCK A; BRADY M
NEUROREHABIL NEURAL REPAIR , 2013, vol. 27, n° 2, p. 133-141
Doc n°: 167289
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1177/1545968312454683
Descripteurs : AF21 - ACCIDENTS VASCULAIRES CEREBRAUX

Limited evidence suggests that visual impairments may influence
outcome after stroke. The degree of recovery from these impairments is poorly
characterized. OBJECTIVES: To describe recovery and to determine whether visual
impairments influence functional outcome and quality of life. METHODS: We
extracted demographic and outcome data from the Virtual International Stroke
Trials Archive (VISTA). We examined horizontal eye movement disorders and
hemianopia using the Best Gaze and Visual domains of the National Institutes of
Health Stroke Scale (NIHSS) and described recovery at 30 and 90 days.
Proportional odds modelling was used to examine the association between
impairments at baseline, modified Rankin Scale (mRS), and European Quality of
Life Score (EQ-5D) at 90 days. RESULTS: Visual impairments were reported in
7,204/11,900 (60.5%) patients at baseline. Complete recovery occurred in
1,398/3,285 (42.6%) and 3,243/7,204 (45.0%) patients by 30 and 90 days
respectively. The burden of persistent visual impairment in survivors was
1,135/4,028 (28.2%) at 30 days and 1,915/9,338 (20.5%) at 90 days. Partial gaze
palsy (P < .0001; OR = 0.81; 95% CI = 0.74-0.87), forced deviation (P < .0001; OR
= 0.48; 95% CI = 0.43-0.53), and complete homonymous hemianopia (P < .0001; OR =
0.67; 95% CI = 0.62-0.73) at baseline were associated with poor mRS at 90 days.
CONCLUSIONS: The rate of recovery was greater in the first month after stroke,
suggesting a potential time frame for interventions. The associations between
visual impairments and poor mRS suggest that these impairments should be
considered in multidisciplinary assessments and interventions.

Langue : ANGLAIS

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