Article

The aim of this study was to describe patterns for gross motor development
by level of severity in a Dutch population of individuals with cerebral palsy
(CP). METHOD: This longitudinal study included 423 individuals (260 males, 163
females) with CP. The mean age at baseline was 9 years 6 months (SD 6y 2mo, range
1-22y). The level of severity of CP among participants, according to the Gross
Motor Function Classification System (GMFCS), was 50% level I, 13% level II, 14%
level III, 13% level IV, and 10% level V. Participants had been assessed up to
four times with the Gross Motor Function Measure (GMFM-66) at 1- or 2-year
intervals between 2002 and 2009. Data were analysed using non-linear mixed
effects modelling. For each GMFCS level, patterns were created by contrasting a
stable limit model (SLM) with a peak and decline model (PDM), followed by
estimating limits and rates of gross motor development. RESULTS: The SLM showed a
better fit for all GMFCS levels than the PDM. Within the SLM, significant
differences between GMFCS levels were found for both the limits (higher values
for lower GMFCS levels) and the rates (higher values for GMFCS levels I-II vs
level IV and for GMFCS levels I-IV vs level V) of gross motor development.
INTERPRETATION: The results validate the existence of five distinct patterns for
gross motor development by level of severity of CP.
CI - (c)The Authors. Developmental Medicine & Child Neurology (c) 2013 Mac Keith
Press.

Langue : ANGLAIS