Article

OBJECTIVE: To assess the odds of reporting low back pain (LBP) as related to
systemic inflammation and obesity. DESIGN: Cross-sectional analysis of the 1999
to 2004 National Health and Nutrition Examination Survey (NHANES). SETTING:
National database analysis. PARTICIPANTS: Population-based sample of 15,322
participants in the 1999 to 2004 NHANES databases. INTERVENTIONS: Not applicable.
MAIN OUTCOME MEASURES: Systemic inflammation was measured by C-reactive protein
(CRP) and fibrinogen. Obesity was quantified by body mass index and waist
circumference (WC). LBP was identified by self-report. Analysis included logistic
regression to assess the odds of reporting LBP as related to systemic
inflammation and obesity. RESULTS: It was hypothesized that obesity and systemic
inflammation would increase the odds of reporting LBP. Participants with elevated
CRP (>3.0mg/dL) had 1.74 (95% confidence interval [CI], 1.04-2.91) greater odds
of reporting LBP. Those who were obese (>/=30kg/m(2)) with elevated CRP had 2.87
(95% CI, 1.18-6.96) greater odds of reporting LBP than those without elevated
CRP. When using WC as the measure of obesity, participants with high WC values
had significantly greater odds of reporting LBP (odds ratio=2.39; 95% CI,
1.09-5.21). CONCLUSIONS: To our knowledge, this is the first study showing that
high levels of CRP may increase the odds of reporting LBP, especially in those
who are obese. These findings warrant further investigation of the interrelations
among obesity, systemic inflammation, and LBP.
CI - Copyright (c) 2013 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS