Article

Progressive visual complaints related to visuospatial disorders, and less often
to visuoperceptual disorders, may be the presenting and isolated manifestation of
a focal degeneration in the posterior cortical areas, called posterior cortical
atrophy (PCA). PCA is a clinical syndrome corresponding to a focal variant of
Alzheimer's disease in 80% of cases. The predominant dysfunction in the
occipitoparietal pathways results in predominant visuospatial disorders,
manifesting primarily as dorsal simultanagnosia, alone or associated with other
symptoms of Balint's syndrome. PCA is rare and affects young patients who are
fully aware of their deficits. Diagnosis of PCA is often delayed, due to
insidious onset and development of symptoms, and to poor awareness of the
condition in the medical community. An earlier diagnosis requires both better
knowledge of PCA among ophthalmologists and neurologists and better recognition
of visual complaints, leading to simple bedside tasks that can tackle the
syndrome.
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Langue : ANGLAIS