Article

The authors aimed to describe how often the allocation method and the statistical
analyses that deal with bilateral involvement are reported in clinical trials for
carpal tunnel syndrome and to determine whether reporting has improved over time.
Forty-two trials identified from recently published systematic reviews were
assessed. Information about allocation method and statistical analyses was
obtained from published reports and trialists. Only 15 trialists (36%) reported
the method of random sequence generation used, and 6 trialists (14%) reported the
method of allocation concealment used. Of 25 trials including participants with
bilateral carpal tunnel syndrome, 17 (68%) reported the method used to allocate
the wrists, whereas only 1 (4%) reported using a statistical analysis that
appropriately dealt with bilateral involvement.
There was no clear trend of
improved reporting over time. Interventions are needed to improve reporting
quality and statistical analyses of these trials so that these can provide more
reliable evidence to inform clinical practice.

Langue : ANGLAIS