Article

Fatigue is a chronic symptom for people with multiple sclerosis
(PwMS). OBJECTIVE: Symptoms of fatigue were investigated during and following a
single exercise session.
METHODS: In all, 58 PwMS and 15 healthy, low-active
controls performed a cycle ergometer incremental exercise test to voluntary
exhaustion. Physiological intensity (expired air and heart rate), perceived
breathlessness, and leg fatigue (Rating of Perceived Exertion [RPE] CR-10 Scale)
were measured during and for 10 minutes following exercise. MEASURES: of baseline
disability (Barthel Index), activity (Physical Activity Scale for the Elderly),
vitality (Subjective Vitality Scale), and general fatigue (Fatigue Severity Scale
[FSS]) were recorded. RESULTS: PwMS had reduced exercise capacity (P = .00 to
.01), but sensations of breathlessness and leg fatigue were the same at voluntary
exercise termination in both groups (P = .09). PwMS with fatigue (FSS >/= 4)
exhibited reduced exercise capacity (P = .03 to .05) but reached the same
physiological intensity, breathlessness, and leg fatigue symptoms at test
termination as nonfatigued peers (P = .16 to .59). During recovery, there was no
difference in observed means between groups, except for leg RPE, which was higher
in the MS group (P = .047) and higher at 3 and 5 minutes after exercise in the
fatigued MS group (P = .02). Physiological markers and breathlessness recovered
at the same rate in both groups (P = .33 to .67). CONCLUSION: Monitoring leg
fatigue symptoms during and through recovery from physical activities may help
guide participation in physical activities for PwMS, particularly in people
managing high levels of fatigue.

Langue : ANGLAIS