Article

The present study explored the impact of cognitive decline on postural control
strategies in older adults with and without cognitive decline from mild cognitive
impairment (MCI) to mild-to-moderate Alzheimer disease (MMAD). We hypothesized
that the cognitive decline affected the postural control leading to higher
bounding limits of COP velocity dynamics. Based on a cross-sectional design, 175
non-faller older adults were recruited in Angers University Hospital, France,
including 50 cognitively healthy individuals [CHI] (mean age 76.42 +/- 4.84
years; 30% women), 64 age- and body mass index-matched participants with MCI
(mean age 77.51 +/- 6.32 years; 39% women), and 61 age- and body mass
index-matched participants with MMAD (mean age 78.44 +/- 3.97 years; 62% women).
For all data collection of postural sway, the participants were asked to maintain
quiet stance on force platform. The postural test consisted of two trials of
quiet stance, with eyes open and with eyes closed. The COP parameters were mean
and standard deviation (SD) of position, velocity and average absolute maximal
velocity (AAMV) in antero-posterior and medio-lateral directions. Overall, the
analysis concerning all COP parameters revealed a significant main effect of
cognitive status on velocity-based variables, with post hoc comparisons
evidencing that SD velocity and AAMV increased with cognitive impairment. The
current findings suggest an active control (or corrective process) of COP
velocity dynamics for CHI, whereas MCI and MMAD are affected by COP movements.
CI - Copyright (c) 2013 Elsevier B.V. All rights reserved.

Langue : ANGLAIS