Article

Cancer treatment-related fatigue is the most prevalent and distressing
symptom of cancer therapy. Interventions to minimize fatigue are needed. The purpose of this study was to examine the relationship between exercise and
fatigue over the first three cycles of chemotherapy in women receiving either
cyclophosphamide, methotrexate, and fluorouracil (CMF) or doxorubicin and
cyclophosphamide (AC) for breast cancer. METHODS: Seventy-two newly diagnosed
women with breast cancer were instructed in a home-based moderate-intensity
exercise intervention. Measures of functional ability, energy expenditure, and
fatigue were obtained at baseline and posttest. Subjects maintained daily records
of four types of fatigue, and exercise duration, intensity, and type. RESULTS:
Exercise significantly reduced all four levels of fatigue (P < 0.01). As the
duration of exercise increased, the intensity of fatigue declined (P < 0.01).
There was a significant carry-over effect of exercise on fatigue, but the effect
lasted only 1 d. The level of fatigue at study entry was not associated with
number of days of exercise or amount of exercise a woman engaged in. CONCLUSIONS:
The impact of exercise on fatigue was significant and suggests the effectiveness
of a low- to moderate-intensity regular exercise program in maintaining
functional ability and reducing fatigue in women with breast cancer receiving
chemotherapy.

Langue : ANGLAIS

Tiré à part : OUI