Article

Numerous randomized controlled trials have been conducted to determine efficacy
of exercise on cancer-related fatigue. However, many trials lacked sufficient
power to demonstrate significant differences, and little is known about how the
effect of exercise differs depending on patient- and intervention-level
characteristics. A meta-analysis was performed to determine whether exercise
reduces fatigue compared with usual care or nonexercise control intervention in
patients with cancer. The authors searched Ovid MEDLINE, EMBASE, PsycINFO, The
Cochrane Central Register of Controlled Trials, and CINAHL. Two authors
independently extracted the data. Randomized controlled trials comparing exercise
with control intervention in cancer patients in which fatigue was quantified were
eligible. Seventy-two randomized controlled trials were identified, 71 in adults
and 1 in children. Exercise had a moderate effect on reducing fatigue compared
with control intervention. Exercise also improved depression and sleep
disturbance. Type of exercise did not significantly influence the effect on
fatigue, depression, or sleep disturbance. Exercise effect was larger in the
studies published 2009 or later. There was only one pediatric study. The results
of this study suggest that exercise is effective for the management of
cancer-related fatigue.

Langue : ANGLAIS