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Validation of GDI, GPS and GVS for use in Parkinson's disease through evaluation of effects of subthalamic deep brain stimulation and levodopa

The Gait Deviation Index (GDI), Gait Profile Score (GPS) and
Gait Variable Scores
(GVSs) have been proposed as measures of gait quality and validated for use with
children with cerebral palsy.
The aim of this study was to extend this validation
to people with Parkinson's disease by evaluating the effects of subthalamic deep
brain stimulation and levodopa on gait. 16 participants had their gait evaluated
with stimulation, medication or a combination of both. The Unified Parkinson's
Disease Rating Scale (UPDRS) showed statistically significant differences in
agreement with previous studies. The GPS and GDI showed similar treatment effects
as did GVS for hip and knee flexion/extension, as assessed with Cohen's d where
medium or large. Overall the results suggest that these gait indices are
sensitive to treatment in this group of patients and that their use in groups
other than children with cerebral palsy is valid.
CI - Copyright (c) 2014 Elsevier B.V. All rights reserved.

Langue : ANGLAIS

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