Article

OBJECTIVES: To report the frequency, severity, and types of comorbidities in
people with Parkinson disease (PD) using a validated self-report comorbidity
screening tool, and to determine the relationship between comorbidity and
functional mobility. DESIGN: A secondary analysis and cross-sectional
observational study design. SETTING: University hospital; outpatient balance
disorders laboratory. PARTICIPANTS: Persons with mild to moderate idiopathic PD
(N=76). INTERVENTION: Not applicable. MAIN OUTCOME MEASURES: The Cumulative
Illness Rating Scale-Geriatric (CIRS-G) and a comprehensive mobility assessment
including gait (distance walked in 3 min), balance (mini-Balance Evaluation
Systems Test), and physical function (Physical Performance Test). RESULTS: All
participants reported comorbidities in addition to their diagnosed PD. The
average +/- SD number of comorbidities was 6.96 +/- 2.0 (range, 2-11), and the
total CIRS-G score +/- SD was 12.7 +/- 4.8. The most commonly reported organ
systems with comorbidity were eyes and ears (89%), psychiatric (68%),
musculoskeletal (64%), lower gastrointestinal (62%), respiratory (60.5%), upper
gastrointestinal (59.2%), and genitourinary (53.9%). The total CIRS-G score was
significantly related to functional mobility: gait (r=-.53, P=.0001), balance
(r=-.43, P=.0003), and physical performance (r=-.36, P=.0041). Of the original 14
organ systems measured, there were 7 systems that, when combined, best predicted
gait performance, 6 systems combined that best predicted balance performance, and
4 systems combined that predicted functional performance. CONCLUSIONS: This study
reports a high frequency of multiple medical system comorbidity in people with
mild to moderate PD. Furthermore, comorbidity scores were associated with
mobility disability: gait, balance, and physical function. Early intervention is
important to delay mobility disability in PD, and we recommend that people with
PD found to have comorbidities should be screened for balance and gait deficits.
CI - Copyright (c) 2014 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS