Article

Thrombolysis with recombinant tissue plasminogen activator (rtPA) is
part of routine acute stroke clinical practice worldwide.
Yet, it is unclear how
rtPA influences specific rehabilitation outcomes, such as motor, cognitive and
communication function.
The present study aimed to collect pilot data
about the effects of rtPA on communication and motor recovery during the first
three months post-rtPA. METHODS: Four individuals who received thrombolysis with
rtPA for a single left hemisphere ischaemic stroke completed an assessment
battery two weeks and three months post-stroke. Information pertaining to allied
health service usage was also investigated. RESULTS: Reliable changes in
assessment scores were observed for lower limb function in two participants with
severe functional limitations. There was no reliable change in lower limb
function for the two milder participants, or for any participants in upper limb
or language function. Service usage varied between participants. Two participants
required extensive inpatient rehabilitation. Three participants required
outpatient or community rehabilitation. CONCLUSIONS: Tailoring of the service
delivery approach may be required for individuals who receive rtPA based on
functional limitations evident post-rtPA. Future research into the impact of rtPA
on motor, cognitive and communication recovery after stroke is vital to inform
rehabilitation programs and optimize outcomes.

Langue : ANGLAIS