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Intraarticular platelet-rich plasma injection in the treatment of knee
osteoarthritis

POURCHO AM; SMITH J; WISNIEWSKI SJ; SELLON JL
AM J PHYS MED REHABIL , 2014, vol. 93, n° Suppl. 11, p. S108-S121
Doc n°: 173472
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1097/PHM.0000000000000115
Descripteurs : DE56 - TRAITEMENTS - GENOU

Intraarticular platelet-rich plasma (PRP) injection has emerged as a promising
treatment for knee osteoarthritis. Studies to date, including multiple randomized
controlled trials, have shown that PRP is a safe and effective treatment option
for knee osteoarthritis. Intraarticular PRP is similar in efficacy to hyaluronic
acid, and seems to be more effective than hyaluronic acid in younger, active
patients with low-grade osteoarthritis. Treatment benefits seem to wane after 6-9
mos. There are numerous PRP treatment variables that may be of importance, and
the optimal PRP protocol remains unclear. Future investigations should control
and analyze the effects of these variables in PRP treatment. High-quality
randomized controlled trials are needed to optimize PRP treatment methods and
better define the role of PRP in osteoarthritis management in the knee and, potentially, in other joints.
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Langue : ANGLAIS

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