Article

Rehabilitation therapy is an important aspect of recovery after volumetric muscle
loss. However, the traditional rehabilitation approach involves a period of rest
and passive loading followed by gradual active loading. Extracellular matrix is a
naturally occurring material consisting of structural proteins that provide
mechanical strength, structural support, and functional molecules with diverse
bioactive properties. There is evidence to suggest that the addition of
aggressive regenerative rehabilitation protocols immediately after surgical
implantation of an extracellular matrix scaffold to an area of volumetric muscle
loss has significant benefits for extracellular matrix remodeling. Rehabilitation
exercises likely provide the needed mechanical signals to encourage cell
migration and site-specific differentiation in the temporal framework required
for constructive remodeling. Herein, the authors review the literature and
present an example of an aggressive rehabilitation program implemented
immediately after extracellular matrix transplantation into a severely injured quadriceps muscle.
- Regenerative rehabilitation
- Régénération

Langue : ANGLAIS