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Are first ventilatory threshold and 6-minute walk test heart rate interchangeable ? A pilot study in healthy elderlies and cardiac patients

Heart rate (HR) at the ventilatory threshold (VT) is often used to
prescribe exercise intensity in cardiac rehabilitation. Some studies have
reported no significant difference between HR at VT and HR measured at the end of
a 6-min walk test (6-MWT) in cardiac patients. The aim of this work was to assess
the potential equivalence between those parameters at the individual level.
METHOD: Three groups of subjects performed a stress test and a 6-MWT: 22 healthy
elderlies (GES, 77 +/- 3.7 years), 10 stable coronary artery disease (CAD)
patients (GMI, 50.9 +/- 4.2 years) and 30 patients with chronic heart failure
(GHF, 63.3 +/- 10 years). We analyzed the correlation, mean bias, 95% confidence
interval (95% CI) of the mean bias and the magnitude of the bias between 6-MWT-HR
and VT-HR. RESULTS: There was a significant difference between 6-MWT and VT-HR in
GHF (99.1 +/- 8.8 vs 91.6 +/- 18.6 bpm, P=0.016) but not in GES and GMI. The
correlation between those 2 parameters was high for GMI (r=0.78, P<0.05), and
moderate for GES and GHF (r=0.48 and 0.55, respectively, P<0.05). The 95% CI of
bias was large (>30%) in GES and GHF and acceptable in GMI (8-12%). CONCLUSION:
6-MWT-HR and VT-HR do not appear interchangeable at the individual level in
healthy elderlies and CHF patients. In CAD patients, further larger studies
and/or the development of other walk tests could help in confirming the interest
of a training prescription based on walking performance, after an exhaustive
study of their cardiometabolic requirements.
CI - Copyright (c) 2014 Elsevier Masson SAS. All rights reserved.

Langue : ANGLAIS

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