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Efficacy of blood flow-restricted, low-load resistance training in women with risk factors for symptomatic knee osteoarthritis

SEGAL N; WILLIAMS GN; DAVIS MC; WALLACE RB; MIKESKY AE
PM & R , 2015, vol. 7, n° 4, p. 376-384
Doc n°: 174473
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.pmrj.2014.09.014
Descripteurs : DE553 - GONARTHROSE

OBJECTIVE: To assess whether concurrent blood flow restriction (BFR) during
low-load resistance training is an efficacious and tolerable means of improving
quadriceps strength and volume in women with risk factors for symptomatic knee
osteoarthritis (OA). DESIGN: Randomized, double-blinded, controlled trial.
SETTING: Exercise training clinical research laboratory. PARTICIPANTS: Women over
age 45 years with risk factors for symptomatic knee OA.
METHODS: Participants
were randomized to either low-load resistance training (30% 1RM) alone (control)
or with concurrent BFR and completed 4 weeks of 3 times per week leg-press
resistance training. Those randomized to BFR wore a cuff that progressively
restricted femoral blood flow over the weeks of training. Intergroup differences
in outcome measures were compared using regression methods, while adjusting for
BMI. MAIN OUTCOME MEASURES: Isotonic bilateral leg press strength, isokinetic
knee extensor strength, and quadriceps volume by magnetic resonance imaging were
assessed before and after participation. Secondary measures included lower limb
muscle power (leg press and stair climb). Knee pain was assessed to determine
tolerance. RESULTS: Of 45 women who consented to study participation, 40
completed the program. There were no significant intergroup differences in
baseline characteristics except that body mass index was lower in the BFR group
(P = .0223). Isotonic 1RM improved significantly more in the BFR group (28.3 +/-
4.8 kg) than in the control group (15.6 +/- 4.5 kg) (P = .0385). Isokinetic knee
extensor strength scaled to body mass increased significantly more in the BFR
group (0.07 +/- 0.03 nm/kg) than in the control group (-0.05 +/- 0.03 nm/kg) (P =
.0048). Changes in quadriceps volume, leg press power, and knee-related pain did
not significantly differ between groups. CONCLUSIONS: Addition of BFR to a 30%
1RM resistance training program was effective in increasing leg press and knee
extensor strength in women at risk for knee OA, in comparison with the same
program without BFR.
CI - Copyright (c) 2015 American Academy of Physical Medicine and Rehabilitation.
Published by Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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