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Brain-computer interface training combined with transcranial direct current stimulation in patients with chronic severe hemiparesis

Brain-computer interface technology has been applied to stroke
patients to improve their motor function. Event-related desynchronization during
motor imagery, which is used as a brain-computer interface trigger, is sometimes
difficult to detect in stroke patients. Anodal transcranial direct current
stimulation (tDCS) is known to increase event-related desynchronization. This
study investigated the adjunctive effect of anodal tDCS for brain-computer
interface training in patients with severe hemiparesis. SUBJECTS: Eighteen
patients with chronic stroke. DESIGN: A non-randomized controlled study. METHODS:
Subjects were divided between a brain-computer interface group and a tDCS-
brain-computer interface group and participated in a 10-day brain-computer
interface training. Event-related desynchronization was detected in the affected
hemisphere during motor imagery of the affected fingers. The tDCS-brain-computer
interface group received anodal tDCS before brain-computer interface training.
Event-related desynchronization was evaluated before and after the intervention.
The Fugl-Meyer Assessment upper extremity motor score (FM-U) was assessed before,
immediately after, and 3 months after, the intervention. RESULTS: Event-related
desynchronization was significantly increased in the tDCS- brain-computer
interface group. The FM-U was significantly increased in both groups. The FM-U
improvement was maintained at 3 months in the tDCS-brain-computer interface
group. CONCLUSION: Anodal tDCS can be a conditioning tool for brain-computer
interface training in patients with severe hemiparetic stroke.

Langue : ANGLAIS

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