Article

For Veterans with posttraumatic stress disorder (PTSD), depression is a highly
comorbid condition. Both conditions have been associated with decreased quality
of life, and research suggests that comorbid PTSD and depression may result in
worse quality of life than PTSD alone. However, research is needed to elucidate
the effect of comorbidity on a broader variety of quality of life domains. In
this study, we used baseline data of 158 male combat Veterans taking part in a
PTSD treatment trial and examined the unique relationships between quality of
life domains and PTSD symptom clusters, major depressive disorder (MDD)
diagnosis, and self-reported depressive symptoms. Veterans with comorbid PTSD-MDD
reported significantly worse satisfaction-related quality of life than those with
PTSD alone, although this finding was largely attributable to PTSD numbing
symptoms. Subsequent analyses comparing the effect of numbing symptoms to
depressive symptoms revealed that depression exerted a stronger influence,
although numbing symptoms were still uniquely associated with quality of life. We
discuss implications for treatment and research, as well as the need to address
negative affect in Veterans with PTSD.

Langue : ANGLAIS