Article

Cognitive benefits obtained from exercise in healthy populations
support the idea that aerobic and resistance training (AT+RT) would confer
benefit for poststroke recovery. However, there is little evidence regarding the
effectiveness of such programs. OBJECTIVE: To evaluate the effects of a 6-month
exercise program of AT+RT on cognition in consecutively enrolled patients with
motor impairments >/=10 weeks poststroke. METHODS: Outcomes were measured before
and after 6 months of AT+RT on 41 patients. Cognition was measured by the
Montreal Cognitive Assessment (MoCA). Secondary measures included evaluation of
gas exchange anaerobic threshold (ATge), body composition by dual energy X-ray
absorptiometry, and depressive symptoms by questionnaire. RESULTS: There were
significant improvements in overall MoCA scores (22.5 +/- 4.5 to 24.0 +/- 3.9, P
< .001) as well as in the subdomains of attention/concentration (4.7 +/- 1.7 to
5.2 +/- 1.3, P = .03) and visuospatial/executive function (3.4 +/- 1.1 to 3.9 +/-
1.1, P = .002). There was a significant reduction in the proportion of patients
meeting the threshold criteria for mild cognitive impairment (MCI) at baseline
compared with posttraining (65.9% vs 36.6%, P < .001). In a linear regression
model, there was a positive association between change in cognitive function and
change in fat-free mass of the nonaffected limbs (beta = .002; P = .005) and
change in attention/concentration and change in ATge (beta = .383; P </= .001),
independent of age, sex, time from stroke, and change in fat mass and depression
score. CONCLUSION: A combined training model (AT+RT) resulted in improvements in
cognitive function and a reduction in the proportion of patients meeting the
threshold criteria for MCI. Change in cognition was positively associated with
change in fat-free mass and ATge.

Langue : ANGLAIS