Article

AIM: To determine if transient neurological abnormalities (TNA) at 9 months
corrected age predict cognitive, behavioral, and motor outcomes at 6 years of age
in extremely preterm infants. METHOD: A cohort of 124 extremely preterm infants
(mean gestational age 25.5wks; 55 males, 69 females), admitted to our unit
between 2001 and 2003, were classified based on the Amiel-Tison Neurological
Assessment at 9 months and 20 months corrected age as having TNA (n=17), normal
neurological assessment (n=89), or neurologically abnormal assessment (n=18). The
children were assessed at a mean age of 5 years 11 months (SD 4mo) on cognition,
academic achievement, motor ability, and behavior.
RESULTS: Compared with
children with a normal neurological assessment, children with TNA had higher
postnatal exposure to steroids (35% vs 9%) and lower adjusted mean scores on
spatial relations (84 [standard error {SE} 5] vs 98 [SE 2]), visual matching (79
[SE 5] vs 91 [SE 2]), letter-word identification (97 [SE 4] vs 108 [SE 1]), and
spelling (76 [SE 4] vs 96 [SE 2]) (all p<0.05).
INTERPRETATION: Despite a
normalized neurological assessment, extremely preterm children with a history TNA
are at higher risk for lower cognitive and academic skills than those with normal
neurological findings during their first year of school.
CI - (c) 2015 Mac Keith Press.

Langue : ANGLAIS