Article

OBJECTIVE: To examine whether inhibitory control measures were associated with
the dual-task cost (DTC) of walking in persons with multiple sclerosis (MS) and
matched controls without MS. DESIGN: Cross-sectional study. SETTING: University
research laboratory. PARTICIPANTS: The sample (N=56) included ambulatory persons
with relapsing-remitting MS
(n=28 [26 women, 2 men]; median Expanded Disability
Status Scale score, 3.0) from the local community and controls
(n=28) matched by
age, sex, body mass index, and education. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: All participants underwent a modified flanker task followed by
4 trials of the timed 25-foot walk. The first 2 trials involved walking as
quickly as possible only (single-task condition), and the second 2 trials
involved walking as quickly as possible while naming alternate letters of the
alphabet (dual-task condition). Walking speed under single- and dual-task
conditions was used to compute a DTC of walking.
RESULTS: Persons with MS
demonstrated a similar DTC of walking compared with matched controls, but
performed more poorly on inhibitory control measures. Interestingly, inhibitory
control measures were not associated with DTC of walking in the MS sample (all
|rho|<.26, P>.19), but were associated with DTC of walking in controls (all
|rho|>.42, P<.03). CONCLUSIONS: Inhibitory control based on modified flanker
performance might not be associated with DTC of walking in persons with MS.
CI - Copyright (c) 2015 American Congress of Rehabilitation Medicine. Published by
Elsevier Inc. All rights reserved.

Langue : ANGLAIS