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Investigating the impact of pain, age, Gross Motor Function Classification System, and sex on health-related quality of life in children with cerebral palsy

FINDLAY B; SWITZER L; NARAYANAN U; CHEN S; FEHLINGS D
DEV MED CHILD NEUROL , 2016, vol. 58, n° 3, p. 292-297
Doc n°: 178551
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1111/dmcn.12936
Descripteurs : AJ23 - PARALYSIE CEREBRALE, AD3 - MOTRICITE, JF - QUALITE DE VIE

AIM: To explore whether health-related quality of life (HRQOL) can be predicted
by pain, age, Gross Motor Function Classification System (GMFCS) level, and sex
in children with cerebral palsy (CP) and whether different pain etiologies have
varying effects on HRQOL. METHODS: Children with CP aged 3 to 19 years and their
caregivers were consecutively recruited. Caregivers reported their child's pain
(Health Utilities Index 3 [HUI3] pain subset) and HRQOL (DISABKIDS
questionnaires). Physicians identified pain etiologies.
A multiple linear
regression model determined whether pain, GMFCS level, sex, and age predicted
HRQOL. An ANOVA evaluated the effects of pain etiologies on HRQOL. RESULTS: Three
hundred and forty-four participants were approached and 87% (n=300) participated.
Sufficient data were available on 248 (72% of total sample). Sixty-six
participants (27%) formed the pain group with HUI3 pain scores of at least 3. The
presence of pain and increasing age significantly negatively predicted HRQOL
(p<0.001, R(2) =0.141), while GMFCS and sex did not. Musculoskeletal deformity
(24%) and hypertonia (18%) were the most frequent pain causes. HRQOL
statistically differed depending on the pain etiology (p=0.028) with
musculoskeletal deformity showing the lowest mean HRQOL. INTERPRETATION: The
presence of pain and increasing age negatively predict HRQOL in CP.
musculoskeletal deformity has the greatest negative impact on HRQOL.
CI - (c) 2015 Mac Keith Press.

Langue : ANGLAIS

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