Article

This prospective study examined the convergent validity and
responsiveness of the EuroQoL-5 Dimensions Health Questionnaire (EQ-5D) utility
weights in stroke survivors at the subacute stage. METHODS: Repeated assessments
were conducted in rehabilitation wards of a medical centre. A study cohort was
recruited from inpatients (n = 478). A total of 342 participants (71.5%)
completed 2 assessments; 1 at ward admission and 1 before hospital discharge.
Outcome measures, including the Barthel Index (BI), Patient Health Questionnaire
(PHQ-9) and EQ-5D, were administered at ward admission and before hospital
discharge. RESULTS: The validity of the EQ-5D utility weights was assessed by
comparison with the scores of the BI and PHQ-9. The absolute values of Pearson
correlation coefficients ranged from 0.40 to 0.52 for the association of EQ-5D
utility weights with BI scores and PHQ-9 scores at admission and before hospital
discharge. The EQ-5D utility weights had a moderate effect size (0.76), moderate
standardized response mean (0.74), and a significant difference (paired t-value =
13.7, p < 0.001) between baseline and follow-up in their ability to detect
changes in the health status of stroke survivors staying in a rehabilitation
ward. CONCLUSION: This study supports the use of the EQ-5D utility weights as a
valid and responsive instrument for performing cost-utility analyses of stroke
survivors, including those with higher levels of dependence, at the subacute
stage.

Langue : ANGLAIS