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Orthobiologics and Knee Osteoarthritis : A Recent Literature Review, Treatment Algorithm, and Pathophysiology Discussion

CRANE DM; OLIVER KS; BAYES MC
PHYS MED REHABIL CLIN N AM , 2016, vol. 27, n° 4, p. 985-1002
Doc n°: 180727
Localisation : Documentation IRR

D.O.I. : http://dx.doi.org/DOI:10.1016/j.pmr.2016.07.004
Descripteurs : DE553 - GONARTHROSE , DE56 - TRAITEMENTS - GENOU

This article reviews the current options in orthobiologics for the clinical
treatment of knee osteoarthritis (OA). We describe a new model of knee OA that
fills the gap in our understanding of it as a purely traumatic and/or
inflammation-induced cartilage degenerative condition, to a current model of
multinodal pathophysiology. We discuss graft choice and patient selection in the
current state of understanding of the treatment of knee OA in a tissue
engineering model with orthobiologics. We present a sample treatment algorithm
and decision nest for deciding how to proceed with patient care.
CI - Copyright (c) 2016 Elsevier Inc. All rights reserved.

Langue : ANGLAIS

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